Top 20 High-Risk Payment Processors for CBD and Supplement Brands (2025)

If you’re running a CBD or supplement brand with subscriptions, you’ve likely been frozen out by Stripe, PayPal, or Square. These payment processors specialize in high-risk verticals — offering real recurring billing, CBD/Hemp merchant approval, and integrations with platforms like Shopify, WooCommerce, and Chargebee. Whether you’re scaling DTC or need international reach, these 20 providers keep your revenue stable and your brand compliant.

See Top Payment Tools
Top 20 High-Risk Payment Processors for CBD and Supplement Brands (2025)
PaymentCloud logo

For CBD Brands Needing Recurring Billing

Processor: PaymentCloud

  • High approval rate for CBD merchants
  • Supports recurring billing models
  • Integrates with Shopify and WooCommerce
Get Started with PaymentCloud
Easy Pay Direct logo

For High-Volume Supplement Sellers

Processor: Easy Pay Direct

  • Specializes in high-risk industries
  • EPD Gateway for seamless transactions
  • Supports multiple shopping carts
Apply with Easy Pay Direct
NMI logo

For Multi-Channel CBD Retailers

Processor: NMI

  • Unified commerce platform
  • Supports ACH, credit, and debit payments
  • Integrates with BigCommerce
Explore NMI Solutions
Durango Merchant Services logo

For Hard-to-Place CBD Businesses

Processor: Durango Merchant Services

  • Over 25 years of industry experience
  • Specializes in high-risk merchant accounts
  • Offers international banking relationships
Start with Durango
Soar Payments logo

For Mid-Risk CBD Enterprises

Processor: Soar Payments

  • Transparent pricing models
  • Excludes ultra-high-risk industries
  • Quick application process
Apply with Soar Payments
PayKings logo

For CBD Brands with Chargeback Concerns

Processor: PayKings

  • Direct network with 20+ banks
  • Specializes in CBD merchant accounts
  • Chargeback mitigation tools
Get Approved with PayKings
Bankful logo

For CBD Startups Seeking Flexibility

Processor: Bankful

  • Supports CBD and hemp industries
  • Subscription billing options
  • Advanced fraud detection
Discover Bankful Solutions
Merchant Stronghold logo

For Global CBD Payment Processing

Processor: Merchant Stronghold

  • Supports international transactions
  • High approval rates for CBD merchants
  • Customized payment solutions
Partner with Merchant Stronghold
National Processing logo

For CBD Businesses Seeking Low Fees

Processor: National Processing

  • Competitive transaction rates
  • No long-term contracts
  • Supports various payment methods
Apply with National Processing
High Risk Pay logo

For CBD Merchants with Credit Challenges

Processor: High Risk Pay

  • Approves poor credit businesses
  • Supports high-risk industries
  • Secure payment gateways
Start with High Risk Pay
SeamlessChex logo

For CBD Brands Needing eCheck Solutions

Processor: SeamlessChex

  • Offers eCheck and ACH processing
  • High approval rates
  • Customizable solutions
Explore SeamlessChex Services
Host Merchant Services logo

For Transparent CBD Payment Processing

Processor: Host Merchant Services

  • No hidden fees
  • CBD and hemp support
  • 24/7 customer support
Sign Up with Host Merchant Services
Payline Data logo

For CBD Businesses Seeking Versatility

Processor: Payline Data

  • Flexible solutions
  • High-risk industry support
  • Wide platform integrations
Checkout Flexible Payment Solution
Instabill logo

For CBD Brands Needing Offshore Options

Processor: Instabill

  • Global merchant access
  • Subscription billing
  • WooCommerce integrations
Apply With Instabill
Organic Payment Gateways logo

For Stripe Refugees Seeking Stability

Processor: Organic Payment Gateways

  • Shopify and Wix support
  • CBD vetting & compliance help
  • Recurring billing included
Switch from Stripe Safely
Inovio logo

For Compliance-First CBD Brands

Processor: Inovio

  • Hosted checkout & recurring billing
  • Fraud detection tools
  • Minimal dev lift required
Streamline Your CBD Billing
GreenLeaf Payment Solutions logo

For Vertically Integrated CBD Sellers

Processor: GreenLeaf Payment Solutions

  • Recurring flows for CBD
  • Onboarding support for supplements
  • Custom checkout tools
Schedule GreenLeaf Setup
Zen Payments logo

For Brands Needing White-Glove Support

Processor: Zen Payments

  • Subscription-friendly checkout
  • Hands-on onboarding
  • Fraud protection built-in
Secure Your CBD Payments
Greenbox POS logo

For CBD Retail + eCommerce Hybrids

Processor: Greenbox POS

  • CBD-native POS and ecommerce
  • Subscription billing support
  • Built-in compliance features
Explore Greenbox Setup
Authorize.Net logo

For Established Brands With Dev Support

Processor: Authorize.Net + High-Risk Partner

  • Recurring billing via API
  • CBD merchant vetting included
  • Modular integration flexibility
Enable CBD Subscriptions

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Frequently Asked Questions

Why can't CBD brands use Stripe or PayPal for subscriptions?

Stripe and PayPal categorize CBD and supplements as high-risk due to federal and banking regulations, often resulting in frozen funds or sudden account termination even for compliant brands.

Which payment processors actually support CBD subscriptions and pass compliance?

Specialized high-risk processors like PaymentCloud, Easy Pay Direct, and NMI are built to handle CBD regulations and recurring billing — with proactive compliance support during onboarding.

What platforms can these processors integrate with?

Many of these processors support Shopify, WooCommerce, Chargebee, and custom stacks via API — allowing seamless billing and checkout flows tailored for high-risk CBD businesses.

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